Tousseyn, T. ; Thathiah, A. ; Jorissen, E. ; Raemaekers, T. ; Konietzko, U. ; Reiß, Karina ; Maes, K.E. ; Snellinx, A. ; Serneels, L. ; Nyabi, O. ; Annaert, W. ; Weskamp, G. ; Blobel, C. ; Saftig, Paul ; Hartmann, D. ; de Strooper, B.:
ADAM10, the rate-limiting protease of regulated intramembrane proteolysis of Notch and other proteins, is processed by ADAMS-9, ADAMS-15, and the gamma-secretase.
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In: J Biol Chem. (2009), Nr. 284, S. 11738-11747
Le Gall, S.M. ; Bobe, P. ; Reiß, Karina ; Horiuchi, K. ; Niu, X.D. ; Lundell, D. ; Gibb, D.R. ; Conrad, D. ; Saftig, Paul ; Blobel, C.P.:
ADAMs 10 and 17 represent differentially regulated components of a general shedding machinery for membrane proteins such as transforming growth factor alpha, L-selectin, and tumor necrosis factor alpha.
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In: Mol Biol Cell. (2009), Nr. 20, S. 1785-1794
Bloch, L. ; Sineshchekova, O. ; Reichenbach, D. ; Reiß, Karina ; Saftig, Paul ; Kuro-o, M. ; Kaether, C.:
Klotho is a substrate for alpha-, beta- and gamma-secretase.
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In: FEBS Lett. (2009), Nr. 583, S. 3221-3224
Huth, T ; Schmidt-Neuenfeldt, K ; Rittger, Andrea ; Saftig, Paul ; Reiß, Karina ; Alzheimer, C:
Non-proteolytic effect of beta-site APP-cleaving enzyme 1 (BACE1) on sodium channel function.
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In: Neurobiol Dis (2009), Nr. 33, S. 282-289
Reiß, Karina ; Saftig, Paul:
The "a disintegrin and metalloprotease" (ADAM) family of sheddases: physiological and cellular functions.
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In: Semin Cell Dev Biol. (2009), Nr. 20, S. 126-137
Schulz, B. ; Prüssmeyer, J. ; Maretzky, T. ; Ludwig, A. ; Blobel, CP. ; Saftig, Paul ; Reiß, Karina:
ADAM10 regulates endothelial permeability and T-Cell transmigration by proteolysis of vascular endothelial cadherin.
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In: Circ Res. (2008), Nr. 102, S. 1192-1201
Maretzky, T. ; Scholz, F. ; Köten, B. ; Proksch, E. ; Saftig, Paul ; Reiß, Karina:
ADAM10-mediated E-cadherin release is regulated by proinflammatory cytokines and modulates keratinocyte cohesion in eczematous dermatitis.
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In: J Invest Dermatol. (2008), Nr. 128, S. 1737-1746
Schulte A ; Schulz, Beate ; Andrzejewski MG ; Hundhausen, Christoph ; Mletzko S ; Achilles J ; Reiß, Karina ; Paliga K ; Weber C ; Rose-John, Stefan ; Ludwig, Andrea:
Sequential processing of the transmembrane Chemokines CX3CL1 and CXCL16 by alpha- and gamma-secretases.
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In: Biophys. Res. Commun. (2007), Nr. 358, S. 233-40
Maretzky, T. ; Schulte, Jan Markus ; Ludwig, Andrea ; Rose-John, Stefan ; Blobel, C. ; Hartmann, D. ; Altevogt, P. ; Saftig, Paul ; Reiß, Karina:
L1 is sequentially processed by two differently activatedmetalloproteases and presenilin/g-secretase regulating neural celladhesion, cell migration and neurite outgrowth.
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Lichtenthaler SF ; Dominguez DI ; Westmeyer GG ; Reiß, Karina ; Haass C ; Saftig, Paul ; De Strooper B ; Seed B:
The cell adhesion protein P-selectin glycoprotein ligand-1 is a substrate for the aspartyl protease BACE1
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In: J Biol Chem (2003), Nr. 278, S. 48713-48719
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