Electroenzymatic CO2 reduction using recombinant CODHs from seafloor habitats recovered via an activity-based screen
Enzymes, the biological catalysts, often feature selectivities or activities unrivaled by the solid catalysts prevalent in industrial settings. A small number of them can be extracted from cultured microbes and exploited for industrial transformations. However, a tremendous enzymatic potential remains largely untapped among the currently uncultured microbial majority. This project aims at accessing this biological resource and demonstrating the enzymatic electrocatalytic activity for the reduction of CO2 (carbon dioxide) to CO (carbon monoxide) at nanostructured electrode surfaces using marine derived environmental CODH (CO-dehydrogenase) enzyme. The work is conducted in cooperation with Prof. Julien Bachmann, FAU; Germany).
This project (ECO2nvert) was part of BioProMare funded by the BMBF (2020-2023).
Involved Staff:
Dr. Stefanie Böhnke-Brandt - Scientist
Rebecca Bährle - PhD Student
Project-relevant publications and presentations:
Bährle, R., Böhnke, S., Englhard, J., Bachmann, J. and Perner, M. (2023). Current status of carbon monoxide dehydrogenases (CODH) and their potential for electrochemical applications. Bioresour. Bioprocess. 10, 84. https://doi.org/10.1186/s40643-023-00705-9
Bährle, R., Böhnke-Brandt, S. and Perner, M. Talk: Catch me if you can - Function-based screening for novel CODH enzymes from hydrothermal vent environments and marine sediments (2023) VAAM - Vereinigung für allgemeine und angewandte Mikrobiologie
Bährle, R., Böhnke-Brandt, S. and Perner, M. Talk: Seeking novel environmental CODHs using funcitonal metagenomic screening und Poster: How to develop a functional-based screeen for seeking novle CODH enzymes from uncultured microbes (2023) FEMS Conference - Federation of European Microbiological Societies
Bährle, R., Böhnke-Brandt, S. and Perner, M. Talk: From environmental CODH enzymes to industrial application: Development of an activity-based screen to identify novel CODHs (2022) YOUMARES 13 - conference for young marine researcher
Bährle, R., Böhnke-Brandt, S. and Perner, M. Talk: Functional Metagenomics as a tool to identify novel CODH enzymes (2022) VAAM - Vereinigung für allgemeine und angewandte Mikrobiologie
