Schumacher, Neele ; :
ADAM17 orchestrates Interleukin-6, TNFα and EGF-R signaling in inflammation and cancer .
In: Biochim Biophys Acta Mol Cell Res (2021), Nr. 1869, S. 119141

Schumacher, Neele ; Yan, K ; Gandraß, Monja ; Müller, M ; Krisp, C ; Häsler, R ; Carambia, A ; Nofer, JR ; Bernardes, JP ; Khouja, M ; Thomsen, I ; Chalupsky, K ; Bolik, J ; Hölscher, C ; Wunderlich, T ; Herkel, J ; Rosenstiel, P ; Schramm, C ; Schlüter, H ; Renné, T ; Mittrücker, HW ; ; Schmidt-Arras, Dirk:
Cell-autonomous hepatocyte-specific GP130 signaling is sufficient to trigger a robust innate immune response in mice .
In: J Hepatol (2021), Nr. 74, S. 407-418

Schwerd, T ; Krause, F ; Twigg ,SRF ; Aschenbrenner, D ; Chen, YH ; Borgmeyer, U ; Müller, M ; Manrique, S ; Schumacher, Neele ; Wall, SA ; Jung, J ; Damm, T ; Glüer, CC ; Scheller, J ; ; Jones, EY ; Laurence, A ; Wilkie, AOM ; Schmidt-Arras, Dirk ; Uhlig, HH:
A variant in IL6ST with a selective IL-11 signaling defect in human and mouse .
In: Bone Res (2020), Nr. 8, S. 24

Schumacher, Neele ; ; Schmidt-Arras, Dirk:
ADAM-Mediated Signalling Pathways in Gastrointestinal Cancer Formation .
In: Int J Mol Sci (2020), Nr. 21, S. 5133

Gleitz, HFE ; Dugourd, AJF ; Leimkühler, NB ; Snoeren, IAM ; Fuchs, SNR ; Menzel, S ; Ziegler, S ; Kröger, N ; Triviai, I ; Büsche, G ; Kreipe, H ; Banjanin, B ; Pritchard, JE ; Hoogenboezem, R ; Bindels, EM ; Schumacher, Neele ; ; Elf, S ; Saez-Rodriguez, J ; Kramann, R ; Schneider, RK:
Increased CXCL4 expression in hematopoietic cells links inflammation and progression of bone marrow fibrosis in MPN. .
In: Blood (2020), Nr. 136, S. 2051-2064

Schumacher, Neele ; :
ADAM17 Activity and IL-6 Trans-Signaling in Inflammation and Cancer .
In: Cancers (Basel) (2019), Nr. 5, S. 11(11)

Schmidt, S ; Schumacher, Neele ; Schwarz, J ; Tangermann, S ; Kenner, L ; Schlederer, M ; Sibilia, M ; Linder, M ; Altendorf-Hofmann, A ; Knösel, T ; Gruber, ES ; Oberhuber, G ; Bolik, Julia ; Rehman, A ; Sinha, A ; Lokau, Juliane ; Arnold, P ; Cabron, Anne-Sophie ; Zunke, Friederike ; Becker-Pauly, Christoph ; Preaudet, A ; Nguyen, P ; Huynh, J ; Afshar-Sterle, S ; Chand, AL ; Westermann J ; Dempsey PJ ; Garbers, Christoph ; Schmidt-Arras, Dirk ; Rosenstiel P ; Putoczki T ; Ernst M ; :
ADAM17 is required for EGF-R-induced intestinal tumors via IL-6 trans-signaling. .
In: J Exp Med (2018), Nr. 215, S. 1205-1225

Cabron, Anne-Sophie ; El Azzouzi, K ; Boß, Melanie ; Arnold, P ; Schwarz, J ; Rosas, M ; Dobert, JP ; Pavlenko, E ; Schumacher, Neele ; Renné, T ; Taylor, PR ; Linder, S ; ; Zunke, Friederike:
Structural and Functional Analyses of the Shedding Protease ADAM17 in HoxB8-Immortalized Macrophages and Dendritic-like Cells. .
In: J Immunol (2018), Nr. 201, S. 3106-3118

Bedau, T ; Schumacher, Neele ; Peters, Florian ; Prox, J ; Arnold, P ; Koudelka, T ; Helm, O ; Schmidt, F ; Rabe, B ; Jentzsch, M ; Rosenstiel, P ; Sebens, S ; Tholey, A ; ; Becker-Pauly, Christoph:
Cancer-associated mutations in the canonical cleavage site do not influence CD99 shedding by the metalloprotease meprin β but alter cell migration in vitro. .
In: Oncotarget (2017), Nr. 8, S. 54873-54888

Arnold P, ; Boll I, ; Rothaug, Michelle ; Pickhinke U, ; Schumacher, Neele ; Frederike Schmidt F, ; Wichert, Rielana ; Schneppenhein J, ; Lokau, Juliane ; Koudelka T, ; Tholey A, ; Rabe, Björn ; Scheller J, ; Garbers, Christoph ; ; Becker-Pauly, Christoph:
Meprin Metalloproteases shed and release soluble Interleukin-6 Receptor for trans-signaling .
In: Sci Rep (2017), Nr. 7, S. 44053

Yan I ; Schwarz J ; Lücke K ; Schumacher, Neele ; Schumacher V ; Schmidt, Stefanie ; Rabe, Björn ; Saftig, Paul ; Donners M ; ; Mittrücker HW ; Chalaris A.:
ADAM17 controls IL-6 signaling by cleavage of the murine IL-6Rα from the cell surface of leukocytes during inflammatory responses. .
In: J Leukoc Biol (2016), Nr. 99, S. 749-760

Schumacher, Neele ; Schmidt, Stefanie ; Schwarz J ; Dohr D ; Lokau, Juliane ; Scheller J ; Garbers, Christoph ; Chalaris A ; ; Rabe, Björn:
Circulating soluble IL-6R but not ADAM17 activation drives mononuclear cell migration into the inflamed area .
In: J Immunol (2016), Nr. 197, S. 3705-3715

Lokau, Juliane ; Nitz R ; Agthe, Maria ; Monhasery N ; Aparicio Siegmund, Samadhi ; Schumacher, Neele ; Wolf J ; Möller-Hackbarth K ; Waetzig GH ; Grötzinger, Joachim ; Müller-Newen G ; ; Scheller J ; Garbers, Christoph:
Proteolytic Cleavage Governs Interleukin-11 Trans-signaling. .
In: Cell Rep (2016), Nr. 14, S. 1761-1773

Schumacher, Neele ; Meyer D ; Mauermann A ; von der Heyde J ; Wolf, Janina ; Schwarz J ; Knittler, Katharina ; Murphy G ; Michalek M ; Garbers, Christoph ; Bartsch JW ; Guo S ; Schacher B ; Eickholz P ; Chalaris-Rißmann, Athena ; ; Rabe, Björn:
Shedding of Endogenous Interleukin-6 Receptor (IL-6R) Is Governed by A Disintegrin and Metalloproteinase (ADAM) Proteases while a Full-length IL-6R Isoform Localizes to Circulating Microvesicles. .
In: J Biol Chem (2015), Nr. 290, S. 26059-26071